Departments
- Bioenergy/GTL & Structural Biology
- Cancer & DNA Damage Responses
- Genome Dynamics
- Radiotracer Development & Imaging Technology
Bioenergy/GTL & Structural Biology Department
Department Head: Kenneth H. Downing
Deputy: Eva Nogales
The Bioenergy/GTL & Structural Biology Department uses a variety of technologies for studying structures of proteins, protein complexes, and other subcellular assemblies in the contexts of cell biology, microbiology and biofuels development. X-ray crystallography, light and electron microscopy, EM tomography and computational modeling provide information that is used to understand basic cellular processes and their regulation. Technologies for high throughput protein labeling, purification and analysis are being developed to further the goals of this work. Also, proteomics approaches are being used to characterize the normal complement of protein complexes within microbial cells and to see how these change in response to stress. Areas of emphasis include microtubule-based structures and transport, proteases involved in neurodegeneration, lipid metabolism, plant cell wall structure and degradation, and microbial structures and stress response.
Scientists in this Department:
Auer, Manfred |
||
Bielicki, John K |
|
|
Butland, Gareth P |
||
Chang, Hang |
||
Comolli, Luis R |
||
Cong, George |
||
Csencsits, Roseann |
||
Downing, Kenneth H |
||
Fuss, Jill O |
||
Glaeser, Robert M |
||
Han, Bong-Gyoon |
||
Han, Ju |
||
Hyman, Joel |
||
Jap, Bing K |
||
Nogales, Eva |
||
Northen, Trent R |
||
Parvin, Bahram |
||
Shin, David S |
Tainer Lab |
|
Siuzdak, Gary E |
Tainer Lab |
|
Tainer, John A |
Tainer Lab |
|
Tauscher, Andrew |
||
Tsutakawa, Susan |
||
Walian, Peter J |
||
Williams, Gareth |
Tainer Lab |
|
Williams, Paul T |
Williams Lab |
|
Yannone, Steven M |
Cancer & DNA Damage Responses Department
Department Head: Priscilla Cooper
Deputy: Andrew Wyrobek
[More Info Coming Soon]
Scientists in this Department:
Ahmed, Mokim K |
Park Lab |
|
Bissell, Mina J |
||
Blakely, Eleanor A |
Blakely Lab |
|
Campisi, Judith |
Campisi Lab |
|
Chen, Frank |
||
Cooper, Priscilla K |
||
Costes, Sylvain V |
||
Garbe, James C |
||
Gray, Joe |
||
Groesser, Torsten |
||
Hang, Bo |
||
Hines, Curtis |
||
Kowhi, Yoshinori |
Kowhi Lab |
|
Kronenberg, Amy |
||
Kuhn, Irene |
||
Kwon, Yongwon |
Mao Lab |
|
LaBarge, Mark |
||
Lowe, Xiu R |
Wyrobek Lab |
|
Mao, Jian-Hua |
||
Mori, Hidetoshi |
||
Mott, Joni D |
||
Park, Catherine C |
Park Lab |
|
Pluth, Janice M |
||
Polyzos, Aris A |
||
Sarker, Altaf |
||
Schild, David |
||
Schwarz, Richard I |
||
Snijders, Antoine M |
Wyrobek Lab |
|
Stampfer, Martha R |
||
Thompson, Albert C |
Blakely Lab |
|
Trego, Kelly S |
||
Tsai, Miaw-Sheue |
||
Wang, Daojing |
Wang Lab |
|
Weier, Ulli |
||
Wiese, Claudia |
||
Wyrobek, Andrew J |
Wyrobek Lab |
|
Yaswen, Paul |
Genome Dynamics Department
Department Head: Susan Celniker
Deputy: Terumi Kohwi-Shigematsu
The Department of Genome Dynamics interrogates the structure and function of genes and genomes using a variety of technologies and organisms. Genomic, cell biological and computational approaches are being used in Drosophila melanogaster, Caenorhabditis elegans, mice and humans with the long-term goal of understanding basic biological mechanisms and human health and disease. Areas of emphasis include developmental transcriptome and proteome analysis, 2D and 3D imaging of gene expression patterns, RNA splicing, chromatin structure and function, chromosome inheritance, protein complex mapping, and genome ontologies.
Scientists in this Department:
Budworth, Helen |
||
Canaria, Christie A |
||
Celniker, Susan E |
Celniker Lab |
|
Chiolo, Irene E |
||
Conboy, John G |
||
Dernburg, Abby F |
Dernburg Lab |
|
Hammonds, Ann S |
Celniker Lab |
|
Han, Hye-Jung |
Kohwi-Shigematsu Lab |
|
Hoskins, Roger A |
Celniker Lab |
|
Karpen, Gary H |
||
Knowles, David W |
Knowles Lab |
|
Kohwi-Shigematsu, Terumi |
Kohwi-Shigematsu Lab |
|
Luo, Kunxin |
Luo Lab |
|
McMurray, Cynthia T |
||
Minoda, Akiko |
||
Zhang, Weiguo |
Radiotracer Development & Imaging Technology Department
Department Head: Stephen E. Derenzo
Deputy: William Jagust
The Department of Radiotracer Development & Imaging Technology uses nuclear tracers to study biochemical processes in living organisms, and develops new tracers and imaging systems. Research includes (1) technology to make radioisotopes more widely available, (2) development of new radiotracers, (3) radiotracer imaging to study and guide the treatment of diseases of the brain and heart, and cancer, (4) radiotracer imaging to enable the development of improved biofuels, (5) scintillation radiation detectors, (6) application-specific detector arrays and readout electronics, and (7) image reconstruction and analysis. Department facilities include a medical cyclotron, a positron emission tomography camera, a single photon emission tomography camera with X-ray CT scanner, and a 1.5T magnetic resonance imaging system.
Scientists in this Department:
Bizarri, Gregori A |
||
Brennan, Kathleen M |
|
|
Buchko, Rostyslav |
||
Budinger, Thomas F |
|
|
Choong, Woon-Seng |
||
Derenzo, Stephen E |
Derenzo Lab |
|
Eberling, Jamie L |
||
Gullberg, Grant T |
||
Gundiah, Gautam |
Derenzo Lab |
|
Huber, Jennifer S |
||
Huesman, Ronald H |
||
Jagust, William J |
||
Janabi, Mustafa |
O'Neil Lab |
|
Janecek, Petr Martin |
||
Kohwi, Yoshinori |
Kohwi Lab |
|
Maltz, Jonathan S |
||
Moses, William W |
||
O'Neil, James P |
O'Neil Lab |
|
Peng, Qiyu |
||
Qi, Jinyi |
||
Taylor, Scott E |
|
|
Vanbrocklin, Henry F |
|
|
Weber, Marvin J |
|
