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The vision of the Life Sciences Division is to advance basic knowledge, and the health of humans and the biosphere, by elucidating the 4-Dimensional dynamics of complex biological systems -- ranging from molecules to microbes to humans.

Research Highlights

New Insight into an Emerging Genome-Editing Tool
Berkeley Lab researchers have produced the first detailed look at the 3D structure of the Cas9 enzyme and how it partners with guide RNA to interact with target DNA. The results should enhance Cas9’s value and versatility as a genome-editing tool. More » 

 

Berkeley Lab Startup Wants to Know: How Damaged is Your DNA?
Exogen can check the DNA health not only of an individual but that of an entire region, thus answering questions on the impact of environmental events. More » 

 

protein complex

 

How a Shape-shifting DNA-repair Machine Fights Cancer
Maybe you’ve seen the movies or played with toy Transformers, those shape-shifting machines that morph in response to whatever challenge they face. It turns out that DNA-repair machines in your cells use a similar approach to fight cancer and other diseases, according to new research led by Berkeley Lab scientists. More »