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Research Project:
Sub-100 ps Time Digitizer for High Throughput PET
Investigators: P. Denes, S. Derenzo,
H. von der Lippe, E. Mandelli, W. Moses
Purpose: Demonstrate feasibility
of doubling PET scanner throughput by using high-precision time-of-flight
measurements to perform simultaneous calibration and detection.
- Goal 1: Develop monolithic time digitizer
with 10 to 100 ps least count
- Goal 2: Integrate the time digitizer
into a complete PET readout system using existing analog front-end
circuits
- Goal 3: Assemble LSO detector modules
with electronics and determine spatial resolution achievable.
Approach and Methods: PET scanner
patient throughput could be doubled if it were possible to perform
simultaneous calibration and measurement. This would be possible
with LSO-based PET scanners by using time-of-flight to determine
the origin of the detected photons (i.e. the radio-pharmaceutical
in the patient or the external calibration source). To make this
possible, a compact time digitizer with ~100 ps sensitivity must
be developed. We will develop this digitizer in 0.25m or 0.18m CMOS
technology, and demonstrate the feasibility of the approach with
LSO detector modules.
CONTACT:
Technology Transfer Department
E.O. Lawrence Berkeley National Laboratory
MS 90-1070
Berkeley, CA 94720
(510) 486-6467 FAX: (510) 486-6457
TTD@lbl.gov
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